IACUC
When performing genotyping in rodents, the least amount of tissue necessary should be removed. All genotyped animals must be uniquely identified to allow the results to be matched to the animal. If animal identification is being performed through the removal of a piece of tissue (e.g., ear punching, toe clipping), that sample of removed tissue should be used for genotyping purposes. Methods that do not permanently alter the animal or produce slight momentary pain should be prioritized, when scientifically applicable.